Human Papilloma virus type 16/18 E6 antibody [C1P5]
GTX20070
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityVirus
Overview
- SupplierGeneTex
- Product NameHuman Papilloma virus type 16/18 E6 antibody [C1P5]
- Delivery Days Customer10
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDC1P5
- Concentration1.2 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThe human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. C1P5 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
- ReactivityVirus
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. Shi M et al., 2012 Oct, J PatholRead more