HYPB/SETD2 antibody, Internal - KO/KD Validated

GeneTex

HYPB/SETD2 antibody, Internal - KO/KD Validated

10

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Goat

IgG

Huntingtons disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Human, Mouse

2°C to 8°C,-20°C

12352203