IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody

GeneTex

IGF1R (phospho Tyr1131) / Insulin Receptor (phospho Tyr1146) antibody

10

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Rabbit

IgG

Phosphorylated

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Human

2°C to 8°C,-20°C

12352203