IgG Heavy Chain Antibody

Biorbyt

IgG Heavy Chain Antibody

16

ImmunoHistoChemistry

Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT (1) (2) IHC-P

Research Use Only

IG217

IgG

Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This mAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

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