GTX129438 ChIP assay Image
GTX129438 ChIP assay Image
Ikaros antibody
GTX129438
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameIkaros antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.65 mg/ml
- IsotypeIgG
- Scientific DescriptionTranscription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A kindred with mutant IKAROS and autoimmunity. Van Nieuwenhove E et al., 2018 Aug, J Allergy Clin ImmunolRead more
- Multiple myeloma immunoglobulin lambda translocations portend poor prognosis. Barwick BG et al., 2019 Apr 23, Nat CommunRead more
- Resources for the Comprehensive Discovery of Functional RNA Elements. Sundararaman B et al., 2016 Mar 17, Mol CellRead more