GTX632359 WB Image
GTX632359 WB Image
IL10 antibody [GT5111]
GTX632359
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameIL10 antibody [GT5111]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDGT5111
- Concentration1.19 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid beta-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimers disease mouse model. Fujita Y et al., 2021 May 12, Sci RepRead more
- Improvement of Colonic Immune Function with Soy Isoflavones in High-Fat Diet-Induced Obese Rats. Luo Q et al., 2019 Mar 22, MoleculesRead more
- Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice. Mendez-Lara KA et al., 2020 Nov 21, Antioxidants (Basel)Read more
- Novel Indole-fused benzo-oxazepines (IFBOs) inhibit invasion of hepatocellular carcinoma by targeting IL-6 mediated JAK2/STAT3 oncogenic signals. Singh AK et al., 2018 Apr 12, Sci RepRead more