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Insulin antibody [3A6] (Biotin)

Research Use Only
GTX40794
GeneTex
ReactivityBovine, Human, Porcine
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    Insulin antibody [3A6] (Biotin)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    3A6
  • Concentration
    0.70 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
  • Reactivity
    Bovine, Human, Porcine
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Plasma estradiol-17beta, cortisol, and insulin concentrations and serum biochemical parameters surrounding puberty in Japanese Black beef bulls with normal and abnormal semen. Weerakoon WWPN et al., 2020 May, Theriogenology
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