Integrin alpha 3 antibody

GeneTex

Integrin alpha 3 antibody

10

Western Blot

Research Use Only

Polyclonal

Chicken

IgY

Integrin alpha-3/beta-1 is a receptor for fibronectin. laminin. collagen. epiligrin. thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 encodes the integrin alpha 3 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 3 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form an integrin that interacts with many extracellular-matrix proteins. The alpha 3 beta 1 integrin is known variously as: very late (activation) antigen 3 (VLA-3). very common antigen 2 (VCA-2). extracellular matrix receptor 1 (ECMR1). and galactoprotein b3 (GAPB3).

Human, Rat

2°C to 8°C,-20°C

12352203