Bio-Connect

ITGA4 antibody, PAb

Research Use Only
ORB67043
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    ITGA4 antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:500-1:1000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to ITGA4.Integrin alpha-4 (ITGA4) is a single-pass type I membrane protein that belongs to the intergrin alphachain family. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. Theyrecognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin.They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S inVCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T inMADCAM1. On activated endothelial cells, integrin VLA-4 triggers homotypic aggregation for mostVLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with targetcells.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203