Bio-Connect

ITGA6 antibody

Research Use Only
ORB153986
Biorbyt
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    ITGA6 antibody
  • Delivery Days Customer
    16
  • Applications Supplier
    WB: 1:500-2000 WB
  • Certification
    Research Use Only
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal antibody to ITGA6. Integrins are alpha / beta heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival (1,2). The integrin family contains at least 18 alpha and 8 beta subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities (3). Integrins not only transmit signals to cells in response to the extracellular environment (outsidein signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (insideout signaling) (1,2).Integrin alpha 6 is a 120 kDa protein with two splice variants, integrin alpha 6, 6A and 6B (3), which function as receptors for laminins on the basal membrane to mediate cellular adhesion events (46). alpha 6 integrins have been shown to play an important role in hematopoietic stem and progenitor cell homing to the bone marrow.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203