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GTX47041 IHC-P Image
GTX47041 IHC-P Image
GTX47041 IHC-P Image

ITGB1BP2 antibody, N-term

Research Use Only
GTX47041
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    ITGB1BP2 antibody, N-term
  • Delivery Days Customer
    10
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.5-1 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a protein with two cysteine and histidine-rich (CHORD) domains, PXXP motifs, YXXI/P motifs, putative SH2 and SH3 domain binding motifs, and an acidic region at the C-terminus that can bind calcium. Two hybrid analysis showed that this protein interacts with the cytoplasmic domain of the beta 1 integrin subunit and is thought to act as a chaperone protein. Studies in the mouse ortholog of this gene indicate that absence of this gene in mouse results in failed cardiac hypertrophy in response to mechanical stress. Alternative splicing results in multiple transcript variants encoding different isoforms, including an isoform that lacks several domains, including one of the CHORD domains. [provided by RefSeq, May 2017]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Endoplasmic reticulum-associated degradation potentiates the infectivity of influenza A virus by regulating the host redox state. Jung KI et al., 2019 May 1, Free Radic Biol Med
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