ITM2C antibody

GeneTex

ITM2C antibody

9

Research Use Only

0.7 mg/ml

IgG

Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.

2°C to 8°C,-20°C

12352203