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ProductsBack/Jagged 1 antibody [4A24]

Jagged 1 antibody [4A24]

Research Use Only
GTX52879
GeneTex
ApplicationsFlow Cytometry, Western Blot, Neutralisation/Blocking
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Product group Antibodies
ReactivityHuman
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Overview

  • Supplier
    GeneTex
  • Product Name
    Jagged 1 antibody [4A24]
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, Western Blot, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    4A24
  • Concentration
    500 ug/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Acute Lymphoblastic Leukemia Cells Inhibit the Differentiation of Bone Mesenchymal Stem Cells into Osteoblasts In Vitro by Activating Notch Signaling. Yang GC et al., 2015, Stem Cells Int
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