JAM-C antibody [4M35]

Catalog number: GTX52881
Brand: GeneTex
Packing: 100 ug
Price: € 434.00
Expected delivery time: 10 days

Product specifications for - JAM-C antibody [4M35]

Product group: Antibodies
Category: Primary Antibodies
Application: Neutralisation/Blocking; Western Blot
Host: Mouse
Target: JAM3
Target description: junctional adhesion molecule 3
Clonality: Monoclonal
Isotype: IgG1
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 500 ug/ml
Storage instructions: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Scientific information: 
Scientific info: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
Clone ID: 4M35
Gene ID: 83700
Swiss prot ID: Q9BX67
Additional information: 
Synonyms: JAM-2; JAM-3; JAMC; JAM-C; Junctional adhesion molecule 3; junctional adhesion molecule C