Bio-Connect

KDM4A antibody, PAb

Research Use Only
ORB66988
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    KDM4A antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to KDM4A.Lysine-specific demethylase 4A (KDM4A) is a histone demethylase that specifically demethylates Lys-9 and Lys-36 residues of histone H3, thereby playing a central role in histone code. KDM4A does not demethylate histone H3 Lys-4, H3 Lys-27 nor H4 Lys-20. KDM4A demethylates trimethylated H3 Lys-9 and H3 Lys-36 residue, while it has no activity on mono-and dimethylated residues. KDM4A has been shown to participate in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruient of histone deacetylases and NCOR1, respectively.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203