Bio-Connect
GTX121246 WB Image
GTX121246 WB Image
GTX121246 WB Image

KDM6A antibody [N2C1], Internal

Research Use Only
GTX121246
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    KDM6A antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.26 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition. Kitajima S et al., 2021 Feb 25, Sci Rep
    Read more
  • A second X chromosome contributes to resilience in a mouse model of Alzheimers disease. Davis EJ et al., 2020 Aug 26, Sci Transl Med
    Read more
  • Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Perrigue PM et al., 2020 Jun 30, Cancers (Basel)
    Read more
  • Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization. Kato H et al., 2020 Apr, Oncogene
    Read more
  • Histone methylation and demethylation are implicated in the transient and sustained activation of the interleukin-1beta gene in murine macrophages. Imuta H et al., 2020 Dec, Heart Vessels
    Read more
  • Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2. Zhang H et al., 2017 Apr 7, Nat Commun
    Read more
  • UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters. Tang QY et al., 2020 Aug 11, Stem Cell Reports
    Read more
  • UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Gozdecka M et al., 2018 Jun, Nat Genet
    Read more