Overview
- SupplierGeneTex
- Product NameKDM6A antibody [N2C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.26 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene is located on the X chromosome and is the corresponding locus to a Y-linked gene which encodes a tetratricopeptide repeat (TPR) protein. The encoded protein of this gene contains a JmjC-domain and catalyzes the demethylation of tri/dimethylated histone H3. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition. Kitajima S et al., 2021 Feb 25, Sci RepRead more
- A second X chromosome contributes to resilience in a mouse model of Alzheimers disease. Davis EJ et al., 2020 Aug 26, Sci Transl MedRead more
- Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Perrigue PM et al., 2020 Jun 30, Cancers (Basel)Read more
- Cancer-derived UTX TPR mutations G137V and D336G impair interaction with MLL3/4 complexes and affect UTX subcellular localization. Kato H et al., 2020 Apr, OncogeneRead more
- Histone methylation and demethylation are implicated in the transient and sustained activation of the interleukin-1beta gene in murine macrophages. Imuta H et al., 2020 Dec, Heart VesselsRead more
- Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2. Zhang H et al., 2017 Apr 7, Nat CommunRead more
- UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters. Tang QY et al., 2020 Aug 11, Stem Cell ReportsRead more
- UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Gozdecka M et al., 2018 Jun, Nat GenetRead more