Ki67 Antibody
ORB534169
Overview
- SupplierBiorbyt
- Product NameKi67 Antibody
- Delivery Days Customer16
- ApplicationsFlow Cytometry
- Applications SupplierFlow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT FACS, IF, IHC-P
- CertificationResearch Use Only
- Clone IDPMKI67-1
- IsotypeIgG
- Scientific DescriptionRequired to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. [UniProt]
- UNSPSC12352203