Overview
- SupplierGeneTex
- Product NameKLF4 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.24 mg/ml
- IsotypeIgG
- Scientific DescriptionTranscription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets. Lin HC et al., 2017 Jan 11, J Agric Food ChemRead more
- Arsenite inhibits the function of CD133+ CD13+ liver cancer stem cells by reducing PML and Oct4 protein expression. Tang H et al., 2016 Oct, Tumour BiolRead more
- Combined Poziotinib with Manidipine Treatment Suppresses Ovarian Cancer Stem-Cell Proliferation and Stemness. Lee H et al., 2020 Oct 6, Int J Mol SciRead more
- DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma. Li HK et al., 2016 Jun 27, Sci RepRead more
- Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation. Chen PY et al., 2013, PLoS OneRead more
- Effect of the natural compound trans-resveratrol on human MCM4 gene transcription. Uchiumi F et al., 2020 Jul, Oncol RepRead more
- Generation and characterization of a human iPSC line from an ALS patient carrying the Q66K-MATR3 mutation. Pollini D et al., 2018 Dec, Stem Cell ResRead more
- K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Hao Z et al., 2017 Jan 13, Nat CommunRead more
- KLF4 is required for suppression of histamine synthesis by polyamines during bone marrow-derived mast cell differentiation. Nishimura K et al., 2020, PLoS OneRead more
- Kruppel-like factor 4 upregulates matrix metalloproteinase 13 expression in chondrocytes via mRNA stabilization. Takeuchi Y et al., 2020 Nov, Cell Tissue ResRead more