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GTX101508 WB Image
GTX101508 WB Image
GTX101508 WB Image

KLF4 antibody

Research Use Only
GTX101508
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    KLF4 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.24 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Antroquinonol, a Ubiquinone Derivative from the Mushroom Antrodia camphorata, Inhibits Colon Cancer Stem Cell-like Properties: Insights into the Molecular Mechanism and Inhibitory Targets. Lin HC et al., 2017 Jan 11, J Agric Food Chem
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  • Arsenite inhibits the function of CD133+ CD13+ liver cancer stem cells by reducing PML and Oct4 protein expression. Tang H et al., 2016 Oct, Tumour Biol
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  • Combined Poziotinib with Manidipine Treatment Suppresses Ovarian Cancer Stem-Cell Proliferation and Stemness. Lee H et al., 2020 Oct 6, Int J Mol Sci
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  • DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma. Li HK et al., 2016 Jun 27, Sci Rep
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  • Down-regulation of the oncogene PTTG1 via the KLF6 tumor suppressor during induction of myeloid differentiation. Chen PY et al., 2013, PLoS One
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  • Effect of the natural compound trans-resveratrol on human MCM4 gene transcription. Uchiumi F et al., 2020 Jul, Oncol Rep
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  • Generation and characterization of a human iPSC line from an ALS patient carrying the Q66K-MATR3 mutation. Pollini D et al., 2018 Dec, Stem Cell Res
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  • K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression. Hao Z et al., 2017 Jan 13, Nat Commun
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  • KLF4 is required for suppression of histamine synthesis by polyamines during bone marrow-derived mast cell differentiation. Nishimura K et al., 2020, PLoS One
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  • Kruppel-like factor 4 upregulates matrix metalloproteinase 13 expression in chondrocytes via mRNA stabilization. Takeuchi Y et al., 2020 Nov, Cell Tissue Res
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