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KLK1 antibody, PAb

Research Use Only
ORB76147
Biorbyt
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityRat
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    Biorbyt
  • Product Name
    KLK1 antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Applications Supplier
    Western blot - 0.1-0.5 μg/ml - Rat - - - Immunohistochemistry(Paraffin-embedded Section) - 0.5-1 μg/ml - Rat - - - By Heat WB, IHC
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    500 ug/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit Polyclonal to KLK1. KLK1(KALLIKREIN 1), also called KLKR, is a protein that in humans is encoded by the KLK1 gene. KLK1 is a member of the peptidase S1 family. KLK1 is a serine protease that generates Lys-bradykinin by specific proteolysis of kininogen-1. The KLK1 gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and its exact cytogenetic location is 19q13.33. The KLK1 gene contains 5 coding exons. And KLK1 is the most centromeric gene in the cluster. Mice lacking tissue kallikrein are unable to generate significant levels of kinins in most tissues and develop cardiovascular abnormalities early in adulthood despite normal blood pressure. The protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
  • Reactivity
    Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203