Overview
- SupplierGeneTex
- Product NameL-Plastin antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.88 mg/ml
- IsotypeIgG
- Scientific DescriptionPlastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- High glucose-induced proteome alterations in hepatocytes and its possible relevance to diabetic liver disease. Chen JY et al., 2013 Nov, J Nutr BiochemRead more
- The killifish visual system as an in vivo model to study brain aging and rejuvenation. Vanhunsel S et al., 2021 Aug 17, NPJ Aging Mech DisRead more