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GTX628803 WB Image
GTX628803 WB Image
GTX628803 WB Image

Lamin B2 antibody [GT144]

Research Use Only
GTX628803
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Lamin B2 antibody [GT144]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clone ID
    GT144
  • Concentration
    0.81 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B2. This gene is in a head-to-tail orientation with the gene for the translocase of inner mitochondrial membrane 13 homolog gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression. Yang SL et al., 2017 Dec 1, Oncotarget
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  • RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. Urban V et al., 2016 Aug 15, J Cell Biol
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  • The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity. Jevtic P et al., 2019 Jun, EMBO Rep
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