LBP antibody [1C7]
GTX54430
ApplicationsFunctional Assay, ImmunoPrecipitation, ELISA
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameLBP antibody [1C7]
- Delivery Days Customer10
- ApplicationsFunctional Assay, ImmunoPrecipitation, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1C7
- Concentration100 ug/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP). [provided by RefSeq, Apr 2012]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203