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GTX84823 IHC-P Image
GTX84823 IHC-P Image
GTX84823 IHC-P Image

Livin antibody [1D12] - Overexpression Validated

Research Use Only
GTX84823
GeneTex
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    Livin antibody [1D12] - Overexpression Validated
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1D12
  • Concentration
    0.36 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203