Bio-Connect

LOXL1 antibody

Research Use Only
GTX114532
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    LOXL1 antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Different expression profiles of the lysyl oxidases and matrix metalloproteinases in human ACL fibroblasts after co-culture with synovial cells. Wang C et al., 2018 Jul, Connect Tissue Res
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  • Effect of mechanical injury and IL-1beta on the expression of LOXs and MMP-1, 2, 3 in PCL fibroblasts after co-culture with synoviocytes. Xu C et al., 2021 Jan 15, Gene
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  • Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol Lett
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  • Novel application of human periodontal ligament stem cells and water-soluble chitin for collagen tissue regeneration: in vitro and in vivo investigations. Jung IH et al., 2012 Mar, Tissue Eng Part A
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