GTX105085 ICC/IF Image
GTX105085 ICC/IF Image
LOXL2 antibody
GTX105085
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameLOXL2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.7 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma. Saito T et al., 2019 May, J Dent ResRead more
- Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis. Alshenibr W et al., 2017 Aug 2, Arthritis Res TherRead more
- Comparative analysis of lysyl oxidase (like) family members in pulmonary fibrosis. Aumiller V et al., 2017 Mar 10, Sci RepRead more
- HIF-1alpha promoted vasculogenic mimicry formation in hepatocellular carcinoma through LOXL2 up-regulation in hypoxic tumor microenvironment. Wang M et al., 2017 Apr 27, J Exp Clin Cancer ResRead more
- LOXL2 Expression Status Is Correlated With Molecular Characterizations of Cervical Carcinoma and Associated With Poor Cancer Survival via Epithelial-Mesenchymal Transition (EMT) Phenotype. Cao C et al., 2020, Front OncolRead more
- LOXL2 promotes aggrecan and gender-specific anabolic differences to TMJ cartilage. Tashkandi MM et al., 2020 Nov 19, Sci RepRead more
- Mechanical injury and IL-1beta regulated LOXs and MMP-1, 2, 3 expression in ACL fibroblasts co-cultured with synoviocytes. Wang C et al., 2020 Aug, Biotechnol LettRead more
- Mechanism for oral tumor cell lysyl oxidase like-2 in cancer development: synergy with PDGF-AB. Mahjour F et al., 2019 May 13, OncogenesisRead more
- Microarray expression profile of mRNAs and long noncoding RNAs and the potential role of PFK-1 in infantile hemangioma. Yang K et al., 2021 Jan 11, Cell DivRead more
- Multiple Functions of Lysyl Oxidase Like-2 in Oral Fibroproliferative Processes. Saxena D et al., 2018 Oct, J Dent ResRead more