Bio-Connect

Lrp2 antibody

Research Use Only
ORB6173
Biorbyt
ApplicationsELISA
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    Lrp2 antibody
  • Delivery Days Customer
    16
  • Applications
    ELISA
  • Applications Supplier
    ELISA: 1:500-1000, IHC-P: 1:100-500, Flow-Cyt: 3ug/Test, ICC: 1:100-500, IF: 1:100-500 FC
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal antibody to Lrp2 which is also known as LRP-2 and gp330 whose expression can be detected in the placenta but it is highly expressive in the absorptive epithelia. It is found in the apical cell. It can perform functions like positive regulation of oligodendrocyte progenitor proliferation and aorta development. In the embryonic neuroepithelium it mediates endocytic uptake and degradation of BMP4 which is required for correct SHH localization in the ventral neural tube and plays a role in patterning of the ventral telencephalon. It binds to the complex composed of beta-amyloid protein 40 and CLU/APOJ and mediates its endocytosis and lysosomal degradation.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203

References

  • Role of serotonin in the regulation of renal proximal tubular epithelial cells. Erikci A et al., 2016 Aug, Ren Fail
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