Macro H2A.2 antibody [N1C1]

GeneTex

Macro H2A.2 antibody [N1C1]

9

Research Use Only

1 mg/ml

IgG

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

2°C to 8°C,-20°C

12352203