Overview
- SupplierGeneTex
- Product NameMAFG antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.53 mg/ml
- IsotypeIgG
- Scientific DescriptionGlobin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. Pradas-Juni M et al., 2020 Jan 31, Nat CommunRead more
- MAFG is a transcriptional repressor of bile acid synthesis and metabolism. de Aguiar Vallim TQ et al., 2015 Feb 3, Cell MetabRead more
- MAFG-driven astrocytes promote CNS inflammation. Wheeler MA et al., 2020 Feb, NatureRead more
- miR-128 Is Implicated in Stress Responses by Targeting MAFG in Skeletal Muscle Cells. Caggiano R et al., 2017, Oxid Med Cell LongevRead more