MAP Kinase antibody, MAb

Biorbyt

MAP Kinase antibody, MAb

10

Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Western blot - 0.25-0.5 μg/ml - Human, mouse, rat, yeast - - - Immunohistochemistry(Paraffin-embedded Section) - 0.4-1 μg/ml - Human, mouse, rat, yeast - - - By Heat Immunocytochemistry - 1 μg/ml - Human, mouse, rat, yeast - - - ICC, WB, IHC

Research Use Only

Monoclonal

Clone: MAPK-YT

100 ug/ml

Mouse

IgG1

Mouse Monoclonal to MAP Kinase. In mammalian cells, a variety of extracellular stimuli generate intracellular signals that converge on a limited number of so-called mitogen-activated protein (MAP) kinase pathways. The central core of each MAP kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific MAPK kinase (MAPKK), which then activates a specific MAPK. Mek1/2 MAPK kinases are essential for mammalian development, homeostasis, and Raf-induced hyperplasia. Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.

Bovine, Human, Monkey, Mouse, Rat, Yeast

2°C to 8°C,-20°C

12352203