MAP4K4 antibody [3C7B5]

GeneTex

MAP4K4 antibody [3C7B5]

10

Western Blot, ELISA

Research Use Only

Monoclonal

3C7B5

Mouse

IgG

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C,-20°C

12352203