MBTPS1 antibody [C1C3]
GTX117475
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameMBTPS1 antibody [C1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.89 mg/ml
- IsotypeIgG
- Scientific DescriptionThe encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Site-1 protease is required for the generation of soluble (pro)renin receptor. Nakagawa T et al., 2017 Apr 1, J BiochemRead more