Bio-Connect

MBTPS1 antibody [C1C3]

Research Use Only
GTX117475
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    MBTPS1 antibody [C1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.89 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Site-1 protease is required for the generation of soluble (pro)renin receptor. Nakagawa T et al., 2017 Apr 1, J Biochem
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