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ProductsBack/MCP1 / CCL2 antibody [2D8]
GTX60582 ELISA Image
GTX60582 ELISA Image
GTX60582 ELISA Image

MCP1 / CCL2 antibody [2D8]

Research Use Only
GTX60582
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rat
Price on request
Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    MCP1 / CCL2 antibody [2D8]
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    2D8
  • Concentration
    1 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human, Monkey, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Endogenous production of C-C motif chemokine ligand 2 by nasopharyngeal carcinoma cells drives radioresistance-associated metastasis. Guo SS et al., 2020 Jan 1, Cancer Lett
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  • Granulocyte Colony Stimulating Factor (GCSF) Can Attenuate Neuropathic Pain by Suppressing Monocyte Chemoattractant Protein-1 (MCP-1) Expression, through Upregulating the Early MicroRNA-122 Expression in the Dorsal Root Ganglia. Liao MF et al., 2020 Jul 11, Cells
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  • Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline. McMillin M et al., 2014 Jul 10, J Neuroinflammation
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  • Recovery From a Myocardial Infarction Is Impaired in Male C57bl/6 N Mice Acutely Exposed to the Bisphenols and Phthalates That Escape From Medical Devices Used in Cardiac Surgery. Shang J et al., 2019 Mar 1, Toxicol Sci
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  • TIM-4 blockade of KCs combined with exogenous TGF-beta injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts. Wu H et al., 2018 Jul, Int J Mol Med
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