Bio-Connect
GTX85121 IHC-P Image
GTX85121 IHC-P Image
GTX85121 IHC-P Image

MD2 antibody [1A2E3]

Research Use Only
GTX85121
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    MD2 antibody [1A2E3]
  • Delivery Days Customer
    10
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1A2E3
  • Concentration
    1 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203