GTX129674 WB Image
GTX129674 WB Image
MED13 antibody
GTX129674
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameMED13 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- CDK-Mediator and FBXL19 prime developmental genes for activation by promoting atypical regulatory interactions. Feldmann A et al., 2020 Apr 6, Nucleic Acids ResRead more
- FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment. Dimitrova E et al., 2018 May 29, ElifeRead more