Melanoma Cell Marker Antibody Cocktail (anti-MART-1 + gp100 + Tyrosinase)

Biorbyt

Melanoma Cell Marker Antibody Cocktail (anti-MART-1 + gp100 + Tyrosinase)

16

ImmunoHistoChemistry

Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT IHC-P, WB

Research Use Only

M2-7C10 + M2-9E3 + HMB45 + T311

IgG

This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

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