GTX102055 IHC-P Image
GTX102055 IHC-P Image
MFN2 antibody [N1N2], N-term
GTX102055
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameMFN2 antibody [N1N2], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A lack of ChREBP inhibits mitochondrial cristae formation in brown adipose tissue. Sakiyama H et al., 2021 Oct, Mol Cell BiochemRead more
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- Enhancement of Mitochondrial Transfer by Antioxidants in Human Mesenchymal Stem Cells. Li CJ et al., 2017, Oxid Med Cell LongevRead more
- Laminar shear stress promotes mitochondrial homeostasis in endothelial cells. Wu LH et al., 2018 Jun, J Cell PhysiolRead more
- Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells. Cheng CT et al., 2016 Sep 1, Cancer ResRead more
- Mitochondrial dynamics in Angiostrongylus cantonensis-infected mouse brain. Lam HYP et al., 2021 Feb, Parasitol IntRead more