GTX128246 WB Image
GTX128246 WB Image
MMP24 antibody
GTX128246
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameMMP24 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A cellular complex of BACE1 and gamma-secretase sequentially generates Abeta from its full-length precursor. Liu L et al., 2019 Feb 4, J Cell BiolRead more
- Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis. Nothdurft S et al., 2020 Nov 19, OncogenesisRead more