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MMP9 antibody [N2C1], Internal

Research Use Only
GTX100458
GeneTex
Product group Antibodies
Price on request
Packing Size
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Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    MMP9 antibody [N2C1], Internal
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.88 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • 3,4-Dihydroxybenzalactone Suppresses Human Non-Small Cell Lung Carcinoma Cells Metastasis via Suppression of Epithelial to Mesenchymal Transition, ROS-Mediated PI3K/AKT/MAPK/MMP and NFkappaB Signaling Pathways. Chao W et al., 2017 Mar 28, Molecules
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  • 3H-1,2-Dithiole-3-Thione Protects Lens Epithelial Cells against Fructose-Induced Epithelial-Mesenchymal Transition via Activation of AMPK to Eliminate AKR1B1-Induced Oxidative Stress in Diabetes Mellitus. Wu TT et al., 2021 Jul 6, Antioxidants (Basel)
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  • Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis. Yeh CY et al., 2015 Jun, Infect Immun
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  • AKR1B1-Induced Epithelial-Mesenchymal Transition Mediated by RAGE-Oxidative Stress in Diabetic Cataract Lens. Wu TT et al., 2020 Mar 25, Antioxidants (Basel)
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  • Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells. Hsu HY et al., 2012, Evid Based Complement Alternat Med
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  • Antitumor effect of kurarinone and underlying mechanism in small cell lung carcinoma cells. Chung TW et al., 2019, Onco Targets Ther
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  • Antroquinonol from Antrodia Camphorata suppresses breast tumor migration/invasion through inhibiting ERK-AP-1- and AKT-NF-kappaB-dependent MMP-9 and epithelial-mesenchymal transition expressions. Lee WT et al., 2015 Apr, Food Chem Toxicol
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  • Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling. Liu Y et al., 2020 Aug 26, Elife
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  • Chaperonin-Containing TCP-1 Promotes Cancer Chemoresistance and Metastasis through the AKT-GSK3beta-beta-Catenin and XIAP-Survivin Pathways. Chang YX et al., 2020 Dec 21, Cancers (Basel)
    Read more
  • Curcumin Inhibits LIN-28A through the Activation of miRNA-98 in the Lung Cancer Cell Line A549. Liu WL et al., 2017 Jun 3, Molecules
    Read more