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GTX134070 WB Image
GTX134070 WB Image
GTX134070 WB Image

MPZ antibody

Research Use Only
GTX134070
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    MPZ antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.75 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain, which are essential for the formation and stabilization of the multilamellar structure of the compact myelin. Mutations in the orthologous gene in human are associated with myelinating neuropathies. A recent study showed that two isoforms are produced from the same mRNA by use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Oct 2015]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Elovl5 is required for proper action potential conduction along peripheral myelinated fibers. Hoxha E et al., 2021 Oct, Glia
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