GTX60514 ELISA Image
MSH6 antibody [5B11]
GTX60514
Overview
- SupplierGeneTex
- Product NameMSH6 antibody [5B11]
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5B11
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203