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GTX104990 IP Image
GTX104990 IP Image
GTX104990 IP Image

MTHFD2 antibody [N1C3]

Research Use Only
GTX104990
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    MTHFD2 antibody [N1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1.16 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Lentivirus-mediated CDglyTK gene-modified free flaps by intra-artery perfusion show targeted therapeutic efficacy in rat model of breast cancer. Zhang J et al., 2019 Sep 14, BMC Cancer
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  • Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability. Lee WD et al., 2021 Jan 5, Cell Metab
    Read more