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GTX101557 WB Image
GTX101557 WB Image
GTX101557 WB Image

mTOR antibody [C3], C-term

Research Use Only
GTX101557
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    mTOR antibody [C3], C-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.38 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Wei RJ et al., 2016 Nov 15, Toxicol Appl Pharmacol
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  • Activity-independent targeting of mTOR to lysosomes in primary osteoclasts. Wang A et al., 2017 Jun 7, Sci Rep
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  • Aluminum-Induced Synaptic Plasticity Impairment via PI3K-Akt-mTOR Signaling Pathway. Li H et al., 2020 Apr, Neurotox Res
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  • Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Peng Q et al., 2019 Dec 12, Aging (Albany NY)
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  • CGRP overexpression does not alter depression-like behavior in mice. Hashikawa-Hobara N et al., 2021, PeerJ
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  • Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J Ethnopharmacol
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  • Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma. Chang CH et al., 2015 Jan 30, Oncotarget
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  • Inflammatory interferon activates HIF-1alpha-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway. Yeh YH et al., 2018 Mar 27, J Exp Clin Cancer Res
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  • Korean red ginseng attenuates hyperglycemia-induced renal inflammation and fibrosis via accelerated autophagy and protects against diabetic kidney disease. Karunasagara S et al., 2020 May 23, J Ethnopharmacol
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  • Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. Wang H et al., 2020 Jan, J Cell Mol Med
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