Overview
- SupplierGeneTex
- Product NamemTOR antibody [C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.38 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Wei RJ et al., 2016 Nov 15, Toxicol Appl PharmacolRead more
- Activity-independent targeting of mTOR to lysosomes in primary osteoclasts. Wang A et al., 2017 Jun 7, Sci RepRead more
- Aluminum-Induced Synaptic Plasticity Impairment via PI3K-Akt-mTOR Signaling Pathway. Li H et al., 2020 Apr, Neurotox ResRead more
- Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Peng Q et al., 2019 Dec 12, Aging (Albany NY)Read more
- CGRP overexpression does not alter depression-like behavior in mice. Hashikawa-Hobara N et al., 2021, PeerJRead more
- Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J EthnopharmacolRead more
- Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma. Chang CH et al., 2015 Jan 30, OncotargetRead more
- Inflammatory interferon activates HIF-1alpha-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway. Yeh YH et al., 2018 Mar 27, J Exp Clin Cancer ResRead more
- Korean red ginseng attenuates hyperglycemia-induced renal inflammation and fibrosis via accelerated autophagy and protects against diabetic kidney disease. Karunasagara S et al., 2020 May 23, J EthnopharmacolRead more
- Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. Wang H et al., 2020 Jan, J Cell Mol MedRead more