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GTX132803 WB Image
GTX132803 WB Image
GTX132803 WB Image

mTOR (phospho Ser2448) antibody

Research Use Only
GTX132803
GeneTex
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Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    GeneTex
  • Product Name
    mTOR (phospho Ser2448) antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.5 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Aluminum-Induced Synaptic Plasticity Impairment via PI3K-Akt-mTOR Signaling Pathway. Li H et al., 2020 Apr, Neurotox Res
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  • Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Peng Q et al., 2019 Dec 12, Aging (Albany NY)
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  • CD133 prevents colon cancer cell death induced by serum deprivation through activation of Akt-mediated protein synthesis and inhibition of apoptosis. Mori Y et al., 2021 May, FEBS Open Bio
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  • CGRP overexpression does not alter depression-like behavior in mice. Hashikawa-Hobara N et al., 2021, PeerJ
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  • Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J Ethnopharmacol
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  • Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. Li J et al., 2020 Jul 15, J Ethnopharmacol
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  • Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. Wang H et al., 2020 Jan, J Cell Mol Med
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  • MicroRNA-223-induced inhibition of the FBXW7 gene affects the proliferation and apoptosis of colorectal cancer cells via the Notch and Akt/mTOR pathways. Liu Z et al., 2021 Feb, Mol Med Rep
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  • mTOR Inhibitors Can Enhance the Anti-Tumor Effects of DNA Vaccines through Modulating Dendritic Cell Function in the Tumor Microenvironment. Chen YL et al., 2019 May 2, Cancers (Basel)
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  • The Inhibition of microRNA-128 on IGF-1-Activating mTOR Signaling Involves in Temozolomide-Induced Glioma Cell Apoptotic Death. Chen PH et al., 2016, PLoS One
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