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GTX15481 IHC-P Image
GTX15481 IHC-P Image
GTX15481 IHC-P Image

MUC1 antibody

Research Use Only
GTX15481
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
Large volume orders?
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Overview

  • Supplier
    GeneTex
  • Product Name
    MUC1 antibody
  • Delivery Days Customer
    10
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Let-7-mediated suppression of mucin 1 expression in the mouse uterus during embryo implantation. Inyawilert W et al., 2015, J Reprod Dev
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  • Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity. Nguyen QH et al., 2018 May 23, Nat Commun
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  • Superovulation at a specific stage of the estrous cycle determines the reproductive performance in mice. Inyawilert W et al., 2016 Dec, Reprod Biol
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