MUC6 Antibody / Gastric Mucin

Biorbyt

MUC6 Antibody / Gastric Mucin

16

ImmunoHistoChemistry

Immunohistochemistry (FFPE): 2-4ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) IHC-P

Research Use Only

MUCN6-2R

IgG

MUC6 or gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2; Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

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