Munc 13-4 antibody [N1N2], N-term

GeneTex

Munc 13-4 antibody [N1N2], N-term

9

Research Use Only

1 mg/ml

IgG

This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq]

2°C to 8°C,-20°C

12352203