Bio-Connect

MYC antibody, PAb

Research Use Only
ORB48021
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rabbit, Rat
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    MYC antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    Western blot - 0.1-0.5 μg/ml - Human - Mouse, Rat - WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    500 ug/ml
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit Polyclonal to MYC. C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
  • Reactivity
    Human, Monkey, Mouse, Rabbit, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203