MYC antibody, PAb
ORB48021
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rabbit, Rat
Overview
- SupplierBiorbyt
- Product NameMYC antibody, PAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWestern blot - 0.1-0.5 μg/ml - Human - Mouse, Rat - WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration500 ug/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRabbit Polyclonal to MYC. C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
- ReactivityHuman, Monkey, Mouse, Rabbit, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203