Nav1.8 Antibody (OASE00190)
OASE00190
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application
Product group Antibodies
ReactivityHuman, Monkey, Mouse, Rat
TargetScn10a
Overview
- SupplierAviva Systems Biology
- Product NameNav1.8 Antibody (OASE00190)
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDS134-12
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID29571
- Target nameScn10a
- Target descriptionsodium voltage-gated channel alpha subunit 10
- Target synonymsNa(V)1.8; Nav1.8; peripheral nerve sodium channel 3; PN3; sensory neuron sodium channel; sodium channel protein type 10 subunit alpha; sodium channel protein type X subunit alpha; sodium channel type X alpha polypeptide; sodium channel voltage-gated type X alpha polypeptide; sodium channel, voltage-gated, type 10, alpha polypeptide; sodium channel, voltage-gated, type X, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.8
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionNav1.8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals.
- ReactivityHuman, Monkey, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203