GTX114119 IHC-P Image
GTX114119 IHC-P Image
NDUFS8 antibody
GTX114119
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameNDUFS8 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.35 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- IBA57 mutations abrogate iron-sulfur cluster assembly leading to cavitating leukoencephalopathy. Ishiyama A et al., 2017 Oct, Neurol GenetRead more
- Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. Lim SC et al., 2016 Jun, FASEB JRead more