Overview
- SupplierGeneTex
- Product NameNF-H antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.71 mg/ml
- IsotypeIgG
- Scientific DescriptionNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis. Pigna E et al., 2019 Feb, EBioMedicineRead more
- Ninjurin 1 mediates peripheral nerve regeneration through Schwann cell maturation of NG2-positive cells. Tomita Y et al., 2019 Nov 12, Biochem Biophys Res CommunRead more